| Therapeutic Area(s) | Neurology |
Lumateperone by Intra-Cellular Therapies Inc., has multiple mechanisms, such as that of a potent serotonin 5-HT2A receptor antagonist; a dopamine receptor phosphoprotein modulator (DPPM), acting as a presynaptic partial agonist and postsynaptic antagonist at dopamine D2 receptors, a dopamine D1 receptor-dependent indirect modulator of glutamate (both NDMA and AMPA), and a serotonin reuptake inhibitor.
| Therapeutic Area(s) | Neurology |
Lemborexant was discovered by Eisai Co. Ltd. in-house scientists. It is a novel investigational small molecule inhibiting orexin signaling by binding competitively to both orexin receptors subtypes (receptor 1 and 2).
| Therapeutic Area(s) | Urology |
Contepo is a novel, potentially first-in-class intravenous investigational antibiotic with a broad spectrum of Gram-negative and Gram-positive activity, including activity against most contemporary multi-drug resistant (MDR) strains, such as ESBL-producing Enterobacteriaceae.